The long-lasting effects and volume-enhancing capabilities of semi-permanent fillers make them an attractive option. They are generally used for deeper creases and wrinkles as well as sculpting the face.
Radiesse
The microspheres in Radiesse create scaffolding that your own collagen will grow around. It will eventually be broken down by the body. However, the collagen your body produces in response to the Radiesse stays. The effects last about a year.
Sculptra
Sculptra's polylactic acid particles help stimulate the body's own collagen production. It is most commonly used off-label to treat the nasolabial folds, and the back of the hands and is approved to treat loss of facial fat in HIV patients. Results are generally seen after two to three treatment sessions and can last up to two years.